Reviews a unique new amide-type local anesthetic recently approved for use in the United States. History of usage in other countries. Reviews mechanism of action of local anesthetics. Familiarizes practitioners with the unique chemical structure and pharmacokinetics of Septocaine. Prescribing protocols for Septocaine including recommended clinical administration and maximum dosages. Clinical impressions of efficacy and specific clinical applications. Research regarding safety and efficacy in various age groups. Potential for higher incidence of parethesia when utilized for block anesthesia.