The incidence of acid reflux disease is increasing dramatically in the United States. Dental professionals are often the first to recognize the symptoms and need to be able to treat the dental sequelae of the disease and make appropriate medical referrals. Overview of anatomy and pathology of GERD. Diagnostic techniques, stepwise approach to treatment including lifestyle modifications, OTC and prescription medications, surgical and non-surgical approaches. Dental and medical sequelae and complications including adenocarcinoma.